Boc-(RS)-3-Amino-3-(3-fluorophenyl)-propionic acid

Boc-(RS)-3-Amino-3-(3-fluorophenyl)-propionic acid - Names and Identifiers

Name	3-(Boc-amino)-3-(3-fluorophenyl)propionic acid
Synonyms	RARECHEM AK HT T308 Boc-3-AMino-3-(3-fluorophenyl)propionic acid 3-(Boc-amino)-3-(3-fluorophenyl)propionic acid 3-N-BOC-AMINO-3-(3-FLUOROPHENYL)PROPIONIC ACID 3-(BOC-AMINO)-3-(3-FLUOROPHENYL)PROPIONIC ACID Boc-DL-3-Amino-3-(3-fluorophenyl)propanoic acid Boc-(RS)-3-Amino-3-(3-fluorophenyl)-propionic acid 3-(tert-Butoxycarbonylamino)-3-(3-fluorophenyl)propionic acid 3-TERT-BUTOXYCARBONYLAMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID 3-[(TERT-BUTOXYCARBONYL)AMINO]-3-(3-FLUOROPHENYL)PROPANOIC ACID 3-[(tert-butoxycarbonyl)amino]-3-(3-fluorophenyl)propanoic acid
CAS	284493-59-0
EINECS	671-590-0
InChI	InChI=1/C14H18FNO4/c1-14(2,3)20-13(19)16-11(8-12(17)18)9-5-4-6-10(15)7-9/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)

Boc-(RS)-3-Amino-3-(3-fluorophenyl)-propionic acid - Physico-chemical Properties

Molecular Formula	C14H18FNO4
Molar Mass	283.3
Density	1.214±0.06 g/cm3(Predicted)
Melting Point	124-126°C
Boling Point	422.1±40.0 °C(Predicted)
Flash Point	209.1°C
Vapor Presure	7.03E-08mmHg at 25°C
pKa	4.26±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.516
MDL	MFCD02090701

Boc-(RS)-3-Amino-3-(3-fluorophenyl)-propionic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Safety Description	24/25 - Avoid contact with skin and eyes.
Hazard Class	IRRITANT

Boc-(RS)-3-Amino-3-(3-fluorophenyl)-propionic acid - Introduction

3-(Boc-amino)-3-(3-fluorophenyl)propionic acid is an organic compound containing a Boc protecting group (tert-butoxycarbonyl) and a 3-fluorophenyl group in its chemical structure. The following is an introduction to its nature, use, formulation and safety information:

Nature:
-Appearance: White solid
-molecular formula: C15H18FNO4
-Molecular weight: 293.31g/mol
-Melting point: About 75-80 degrees Celsius
-Solubility: Soluble in polar organic solvents (such as acetic acid, methanol, dimethylformamide), insoluble in non-polar organic solvents (such as methane, ethane).

Use:
3-(Boc-amino)-3-(3-fluorophenyl)propionic acid is a commonly used organic synthesis intermediate, which is widely used in the fields of medicine and pesticide. It can be used as a synthetic intermediate for antibiotics, drugs and bioactive molecules.

Method:
The preparation method of 3-(Boc-amino)-3-(3-fluorophenyl)propionic acid generally uses the means of chemical synthesis. The specific preparation steps may vary depending on the experimental conditions, but usually include the following steps:
1. 3-fluorophenylcarboxylic acid reacts with Boc-amino to generate 3-(Boc-amino) benzoic acid.
2.3-(Boc-amino) benzoic acid is esterified with appropriate acid anhydride to generate 3-(Boc-amino)-3-(3-fluorophenyl)propionic acid.

Safety Information:
- 3-(Boc-amino)-3-(3-fluorophenyl)propionic acid should be kept away from fire and oxidant, and avoid contact with strong acid, strong alkali and strong oxidant.
-During handling and storage, good ventilation should be provided and appropriate protective gloves, goggles and face shields should be worn.
-If inhaled or exposed to the compound, immediately stay away from the source and seek medical help.
-Please store properly and observe relevant safety regulations.

Last Update：2024-04-09 19:05:48